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fully human monoclonal antibody 

  • fully human monoclonal antibody 

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Creative Biolabs has built up HAIL [Human Antibody Immune Library] technology to developfully human monoclonal antibodies. In this technology, instead of immunizing humans [which is ethically impossible], strong immune responses and high affinity antibodies are generated by immunizing humanized mice. After that, a phage display human antibody library is constructed to select high-affinity antibodies against the immunogens. The resultant antibodies are fully human that experience affinity maturation in vivo.

http://www.creative-biolabs.com/full-human-antibody-from-humanized-mouse...

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